• Physiological research · Jan 2008

    Review

    Mechanisms of neurogenic pulmonary edema development.

    • J Sedý, J Zicha, J Kunes, P Jendelová, and E Syková.
    • Institute of Experimental Medicine ASCR, Prague, Czech Republic.
    • Physiol Res. 2008 Jan 1;57(4):499-506.

    AbstractNeurogenic pulmonary edema is a life-threatening complication, known for almost 100 years, but its etiopathogenesis is still not completely understood. This review summarizes current knowledge about the etiology and pathophysiology of neurogenic pulmonary edema. The roles of systemic sympathetic discharge, central nervous system trigger zones, intracranial pressure, inflammation and anesthesia in the etiopathogenesis of neurogenic pulmonary edema are considered in detail. The management of the patient and experimental models of neurogenic pulmonary edema are also discussed.

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