• Pain Pract · Feb 2025

    Comparative Study

    The comparison of spread of methylene blue after the Pericapsular Nerve Group block and a double injection selectively targeting the articular branches to the anterior hip capsule in human cadavers.

    • Rachel J H Smits, TanEdward C T HECTHDepartment of Surgery, Radboudumc, Nijmegen, The Netherlands., Luuk R van den Bersselaar, Anne de Bruijn, Eva Hendriksen, VissersKris C PKCPDepartment of Anesthesiology, Pain and Palliative Medicine, Radboudumc, Nijmegen, The Netherlands., Kim T E Olde Dubbelink, and Selina E I van der Wal.
    • Department of Anesthesiology, Pain and Palliative Medicine, Radboudumc, Nijmegen, The Netherlands.
    • Pain Pract. 2025 Feb 1; 25 (2): e70002e70002.

    ObjectivesIn this study, the spread of methylene blue was compared between an ultrasound-guided Pericapsular Nerve Group (PENG) block and a double injection technique, where the approach towards the inferomedial acetabulum was added to the latter.MethodsThe two techniques were performed in 11 fresh frozen cadavers. The spread was measured after anatomical dissection in which the supplying femoral and obturator nerves were identified.Results And ConclusionOur study demonstrates adequate staining of the iliac bone with comparable distal and medial spread in both techniques, indicating that the PENG block with a single injection is adequate in blocking the hip capsule with 10 mL local anesthetics. Staining of the femoral nerve occurred in 2/6 specimens after the PENG block, and staining of the obturator nerve in 1 specimen in each group.© 2025 The Author(s). Pain Practice published by Wiley Periodicals LLC on behalf of World Institute of Pain.

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