• Ting Jiang, Xinming Wang, Lingli Zheng, Tao Ren, Yan Li, and Jing Li.
• School of Clinical Medicine, Chengdu Medical College, Chengdu, Sichuan Province, China.
• Medicine (Baltimore). 2025 Jan 17; 104 (3): e41067e41067.

AbstractChemotherapy is one of the main treatments for breast cancer patients. However, chemotherapy-related nausea and vomiting can significantly reduce patients' quality of life and lead to electrolyte disturbance and metabolic imbalance in severe cases. Therefore, to identify the risk factors for nausea and vomiting during chemotherapy in these patients is very important. This retrospective study included 113 patients with breast cancer undergoing chemotherapy and used antiemetic drugs hospitalized in First Affiliated Hospital of Chengdu Medical College between January 1, 2021, and January 1, 2023. Of these, 26 (23.01%) patients developed nausea and vomiting. The univariate and multivariate logistics regression analyses showed that patients combined with diabetes, hypertension, chronic hepatitis B, >65 years of age, >8 cycles of chemotherapy, and had a history of nausea and vomiting are the risk factors for nausea and vomiting. However, due to the limited sample size and some risk factor data missing from this study, further prospective studies are needed to improve and verify.Copyright © 2025 the Author(s). Published by Wolters Kluwer Health, Inc.

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