• Luna Sánchez, Bárbara Lanis, Nicolás Meza, and Gustav Rohde.
• Escuela de Medicina, Universidad de Valparaíso, Valparaíso, Chile.
• Rev Med Chil. 2024 Nov 1; 152 (8): 856866856-866.

UnlabelledNo consensus has been reached about how cognitive performance evolves in patients receiving hemodialysis (HD).Aimto analyze the cognitive performance of patients with end-stage chronic kidney disease (CKD) undergoing conservative medical management or HD.MethodsWe conducted a cross-sectional study. The cognitive performance of both groups was assessed through the INECO Frontal Screening (IFS) instrument.Results6 patients were analyzed in each group (n= 12). A significant difference was observed for the total IFS score, with 14.4±6.29 points in the HD group and 21.5±3.96 points in the conservative management group (p<0.05). Regarding the specific domains of the IFS, a significant difference was found in the domain of verbal inhibitory control, with an average of 1.83±1.17 points in the HD group and 4±0.89 points in the conservative management group (p<0.05). No associations were elucidated on the abbreviated MMSE, ACE-III, TMT-A and B, Grober and Buschke Test, Stroop Test and Boston Test Nomination Test.ConclusionPatients with terminal CKD on HD (even those with a normal MMSE result) show an impairment in their executive functions compared to those who underwent conservative management.

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