• Natalia Rebolledo, Pedro Ferrer-Rosende, Marcela Reyes, Smith TaillieLindseyLCarolina Population Center, Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., and Camila Corvalán.
• Center of Research in Food Environment and Prevention of Obesity and Non-Communicable Diseases (CIAPEC), Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.
• Bmc Med. 2025 Jan 27; 23 (1): 4646.

BackgroundChile's Food Labelling Law was implemented in three phases with increasingly stricter limits. After initial implementation, sugars and sodium decreased in packaged foods, with no significant changes for saturated fats. It is unclear whether full implementation is linked with further reformulation or if producers reversed changes due to consumers' preferences. This study examines changes in the proportion of "high in" products and the nutrient content of packaged foods during the Law's three phases.MethodsThis repeated cross-sectional study included the best-selling packaged foods and beverages during 2015-2020. We analyzed the proportion of products classified as "high in" critical nutrients using the final phase cutoffs and examined changes in the content of calories, sugars, sodium, and saturated fats in the three phases. To assess the changes in proportions, we used Firth's bias-reduced logistic regression models and the Cochran-Armitage test for trends. Quantile regression was used to evaluate changes in nutrient content.ResultsThe proportion of "high in" products decreased from 70.8 to 52.5% after the final phase (p < 0.001). The proportion of "high in" sugars products decreased across all sweet food and beverage groups (p < 0.001), except for candies (- 4.5 percentage points (pp), p = 0.09). The largest reductions occurred in sweet spreads and breakfast cereals (- 44.3 and - 40.4 pp, respectively, p < 0.001). For the proportion of "high in" sodium, reductions occurred in all savory food groups (p < 0.001), except cheeses and ready-to-eat meals (p < 0.24), with the largest decreases in savory baked products and non-sausage meat products (- 40.4 and - 38.9 pp, respectively, p < 0.001). Reductions in "high in" saturated fats and energy were less consistent, with the largest decreases in nuts and snacks and savory spreads (- 22.2 and - 20.0 pp, respectively, p < 0.001) and savory baked products and breakfast cereals (- 32.8 and - 25.7 pp, respectively, p < 0.001), respectively. After full implementation, most sweet categories showed left shifts in sugars distribution, except for candies. Similarly, most savory categories showed left shifts for sodium, except savory spreads and ready-to-eat meals. Changes increased as regulation limits tightened (p for trend < 0.001).ConclusionsAfter fully implementing Chile's law, the proportion of "high in" products and the content of critical nutrients decreased in all food and beverage categories. The largest changes occurred for sodium in savory foods and sugars in sweet foods/beverages. Stricter regulatory limits were associated with decreases in critical nutrient content over time.© 2025. The Author(s).

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