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- Ayane Higashi, Hiroto Inoue, Hiroshi Matsumoto, Soichiro Tani, Kenji Isokawa, Hiroyuki Aoyama, Shuhei Shintani, Takayuki Imai, Masashi Ohno, Hidenori Kimura, Toru Miyake, Atsushi Nishida, Ryoji Kushima, Masaji Tani, and Osamu Inatomi.
- School of Medicine, Shiga University of Medical Science, Japan.
- Intern. Med. 2025 Feb 1.
AbstractAlthough sarcoid-like reactions are uncommon in colorectal cancer, they can coexist with other cancers. We herein report a 50-year-old woman with sigmoid adenocarcinoma and osseous sarcoid-like reactions that resembled metastases. Positron emission tomography-computed tomography revealed an uptake in the iliac bone and para-aortic lymph nodes. The depth of invasion indicates non-metastatic lesions. Bone and lymph node biopsies revealed epithelioid non-caseating granulomas with bone trabeculae, resulting in a final diagnosis of pathological T2N2aM0, Stage IIIB. When the expected depth of invasion differs from that of typical bone metastases, colorectal cancer-associated bone lesions should be evaluated for sarcoid-like reactions.
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