• Br J Anaesth · Feb 2025

    Editorial

    The misunderstood P-value: why statistical significance is not enough in clinical practice.

    • Ebadullah S Ahmed and Mohsin N Butt.
    • Department of Anaesthesiology, Aga Khan University, Karachi, Pakistan.
    • Br J Anaesth. 2025 Feb 4.

    AbstractP-values have traditionally guided clinical research, but over-reliance on them can lead to misinterpretation and poor decision-making. This article highlights common misconceptions about P-values and suggests incorporating the minimum clinically important difference (MCID) along with other metrics such as effect sizes and Bayesian methods. Evidence-based practice is essential in anaesthesiology, and research findings should be evaluated in the context of patient outcomes to guide clinical decisions.Copyright © 2025 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.

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