• J D Fortenberry, E J Brizendine, B P Katz, K K Wools, M J Blythe, and D P Orr.
• Department of Pediatrics, Indiana University School of Medicine, Indianapolis, USA.
• Sex Transm Dis. 1999 Jan 1;26(1):26-32.

ObjectiveTo identify factors associated with subsequent sexually transmitted infection (STI) (within 1 year of initial infection) due to Chlamydia trachomatis, Neisseria gonorrhoeae or Trichomonas vaginalis.DesignProspective cohort study.SettingA sexually transmitted diseases clinic and four community-based primary care clinics for adolescents.ParticipantsFemale patients (ages 15 to 19 years) with initial diagnosis of chlamydia, gonorrhea, or trichomonas.Main Outcome MeasuresSubsequent infection by chlamydia, gonorrhea, or trichomonas.ResultsMore than 40% of subjects were subsequently infected by at least one STI. Reinfection was common, but infections with sexually transmitted organisms other than the initial infecting organism were also common. Predictors of subsequent infection were black race, gonorrhea as the initial infection, two or more sex partners in the previous 3 months, and inconsistent condom use.ConclusionsSubsequent STI frequently follow an initial STI, but there is substantial variation in the causal organism. These data suggest the importance of comprehensive STI prevention programs for adolescents rather than organism-specific interventions.

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