• Pacing Clin Electrophysiol · Mar 2013

    Case Reports

    A life-threatening flecainide overdose treated with intravenous fat emulsion.

    • Heather Ellsworth, Samuel J Stellpflug, Jon B Cole, Joseph A Dolan, and Carson R Harris.
    • Department of Emergency Medicine, Regions Hospital, St. Paul, MN 55101, USA. heatherellsworth9@gmail.com
    • Pacing Clin Electrophysiol. 2013 Mar 1;36(3):e87-9.

    AbstractFlecainide is a Vaughan Williams Class Ic antidysrhythmic associated with PR, QRS, and QTc prolongation on the electrocardiogram and development of life-threatening cardiac toxicity in overdose. The cornerstone of treatment is fluid resuscitation and the administration of magnesium and sodium bicarbonate. We report a case of flecainide overdose associated with life-threatening hemodynamic compromise successfully treated with intravenous fat emulsion (IFE) therapy. IFE should be considered as a novel adjunctive therapy in patients with life-threatening toxicity following flecainide overdose.©2012, The Authors. Journal compilation ©2012 Wiley Periodicals, Inc.

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