• Neurologist · May 2005

    Case Reports

    Herpes simplex encephalitis. Is anticoagulation safe?

    • Pascal M Jabbour and Steven G Ojemann.
    • Department of Neurosurgery, Thomas Jefferson University Hospital, Philadelphia, PA 19131, USA. pascal.jabbour@mail.tju.edu
    • Neurologist. 2005 May 1;11(3):187-9.

    BackgroundHerpes simplex encephalitis (HSE) still carries a high morbidity and mortality.Review SummaryThe authors report a 27-year-old patient who presented with an HSE manifested by a high temperature, seizures, and headaches. His hospitalization course was complicated by a pulmonary embolism. After anticoagulation was started, the patient developed a right temporal hematoma at the same region of the abnormal signal on magnetic resonance imaging. The patient underwent a craniotomy and evacuation of the hematoma with an uneventful postoperative outcome.ConclusionThe safety of anticoagulation in HSE has not been raised in the literature previously, and it needs further study.

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