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Anesteziol Reanimatol · Jan 2011
Clinical Trial[Cholinesterase blockers in anesthesiology: a replenishment of former arsenal].
- A A Buniatian, V I Stamov, V M Mizikov, and A V Peĭkarova.
- Anesteziol Reanimatol. 2011 Jan 1(1):4-8.
AbstractCholinesterase blockers are widely used in various fields of clinical medicine. In anesthesiology they are used for the means of decurarisation, as well as for performance of central segmental blockades. In recent years, along with the most frequently used neostigmine again an opportunity arose to use the well-known galantamine. A brief overview of the pharmacological properties of galantamine is completed by the study of its efficacy and safety in 30 patients (first group) who underwent general anesthesia with total myoplegia at a range of abdominal surgeries. The comparison group (second group) included 30 patients who were applied neostigmine. The method of clinical functional evaluation, the accelerometry and frontal electromyography confirmed that galantamine although inferior to neostigmine in efficiency, has a higher safety threshold.
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