• Melissa L McCarthy, Ellen J MacKenzie, Dennis R Durbin, Mary E Aitken, Kenneth M Jaffe, Charles N Paidas, Beth S Slomine, Andrea M Dorsch, Ronald A Berk, James R Christensen, Ru Ding, and CHAT Study Group.
• Department of Emergency Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. mmccarth@jhmi.edu
• Arch Phys Med Rehabil. 2005 Oct 1;86(10):1901-9.

ObjectivesTo assess the reliability and validity of the Pediatric Quality of Life Inventory, version 4.0 (PedsQL), and to compare it with that of the Behavior Rating Inventory of Executive Function (BRIEF) among children with traumatic brain injury (TBI).DesignProspective cohort study that documented the health-related quality of life of 391 children at 3 and 12 months postinjury.SettingFour level I pediatric trauma centers.ParticipantsChildren (age range, 5-15 y) hospitalized with a TBI or an extremity fracture.InterventionsNot applicable.Main Outcome MeasuresParent-reported PedsQL and BRIEF scale scores.ResultsBoth the PedsQL and BRIEF scales showed good internal consistency (PedsQL alpha range, .74-.93; BRIEF alpha range, .82-.98) and test-retest reliability (PedsQL r range, .75-.90; BRIEF r range, .82-.92), respectively. Factor analysis revealed that most PedsQL items loaded most highly on their conceptually derived scale. The PedsQL cognitive function scale detected the largest differences among groups of children with varying severities of TBI as well as parents' assessment of change in cognition postinjury.ConclusionsAlthough the reliability of the 2 instruments is comparable, the PedsQL discriminates better among children with TBI. The PedsQL is a promising instrument for measuring the health of children after TBI.

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