• Anesthesia and analgesia · Mar 2005

    Case Reports

    Hyperkalemic cardiac arrest after cardiopulmonary bypass in a child with unsuspected duchenne muscular dystrophy.

    • Aruna Nathan, Arjunan Ganesh, Rodolfo I Godinez, Susan C Nicolson, and William J Greeley.
    • Department of Anesthesiology and Critical Care Medicine, The Children's Hospital of Philadelphia, PA 19104-4399, USA.
    • Anesth. Analg. 2005 Mar 1;100(3):672-4, table of contents.

    AbstractAdverse reactions to volatile anesthetics and depolarizing muscle relaxants can occur in patients with Duchenne muscular dystrophy (DMD) resulting in acute rhabdomyolysis and hyperkalemia. We report a case of hyperkalemic cardiac arrest after cardiac surgery using cardiopulmonary bypass in a child with unsuspected DMD. Early diagnosis and management of hyperkalemia resulted in a successful outcome. Genetic testing confirmed the diagnosis of DMD. We recommend a thorough preoperative investigation, including creatine kinase estimation, in children with a history of unexplained motor delay.

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