• Anesthesia and analgesia · Apr 2007

    Randomized Controlled Trial

    The effect of epidural anesthesia with different concentrations of ropivacaine on sevoflurane requirements.

    • Jie Zhang, Wei Zhang, and Bin Li.
    • Department of Anesthesiology, The First Affiliated Hospital of ZhengZhou University, No. 1 East-JianShe Road, ZhengZhou 450052, China. joannyzh@hotmail.com
    • Anesth. Analg. 2007 Apr 1;104(4):984-6.

    BackgroundWe evaluated sevoflurane requirements during combined general-epidural anesthesia with different concentration of ropivacaine.MethodsFifty-six patients were randomly divided into three groups to epidurally receive saline, 0.2% ropivacaine or 1% ropivacaine. Sevoflurane concentration was adjusted to maintain certain anesthesia depth. BIS values and end-tidal sevoflurane concentrations were recorded at time points of pre-intubation and 5 min, 10 min, 15 min, 20 min, 25 min, 30 min after intubation.ResultsEnd-tidal sevoflurane was significantly lower in the group receiving higher concentration of sevoflurane.ConclusionsEpidural anesthesia can decrease sevoflurane requirements to a larger extent when a higher concentration of ropivacaine was applied.

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