• Jae Eun Choi, Ga Na Oh, Jong Yeob Kim, Soo Hong Seo, Hyo Hyun Ahn, and Young Chul Kye.
• Department of Dermatology, College of Medicine, Korea University , Seoul , Korea.
• J Dermatolog Treat. 2014 Aug 1;25(4):299-303.

BackgroundNonablative fractional photothermolysis has been reported to show early promise in the treatment of hypertrophic scars, but there are few reports on ablative fractional photothermolysis for the treatment of hypertrophic scars.AimTo evaluate and compare the efficacy and safety of Er:YAG fractional laser (EYFL) and CO2 fractional laser (CO2FL) for treatment of hypertrophic scars.MethodsThirteen patients with hypertrophic scars were treated with 2,940 nm EYFL, and ten were treated with 10,600 nm CO2FL. An independent physician evaluator assessed the treatment outcomes using Vancouver scar scale (VSS) and 5-point grading scale (grade 0, no improvement; grade 1, 1-25%; grade 2, 26-50%; grade 3, 51-75%; grade 4, 76-100% improvement). Patients are queried about their subjective satisfaction with the treatment outcomes.ResultsAfter the final treatment, average percentage changes of VSS were 28.2% for EYFL and 49.8% for CO2FL. Improvement was evident in terms of pliability, while insignificant in terms of vascularity and pigmentation. Based on physician's global assessment, mean grade of 1.8 for EYFL and 2.7 for CO2FL was achieved. Patient's subjective satisfaction scores paralleled the physician's objective evaluation.ConclusionCO2FL is a potentially effective and safe modality for the treatment of hypertrophic scars, particularly in terms of pliability.

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