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Comparative Study
End-tidal partial pressure of CO2 as an estimate of arterial partial pressure of CO2 during various ventilatory regimens in halothane-anesthetized dogs.
- C E Hightower, A L Kiorpes, H C Butler, and M R Fedde.
- Am. J. Vet. Res. 1980 Apr 1;41(4):610-2.
AbstractThe correlation between end-tidal partial pressure of CO2 (PETCO2) and arterial PCO2 (PaCO2) was studied in six halothane-anesthetized dogs maintained under four different ventilatory regimens: (A) spontaneous breathing; (B) assisted positive-pressure ventilation; (C) intermittent manual inflation; and (D) ventilator-controlled breathing. For procedures A, B, and D together, there was a strong correlation between PETCO2 and PaCO2 (r = 0.8) that was highly significant at P less than 0.0001 for PETCO2 values between 31.3 and 61 mm of Hg. In spontaneous and controlled breathing, PETCO2 is representative of PaCO2 and provides a useful noninvasive tool for monitoring the patient maintained under general anesthesia. Furthermore, data suggest that any ventilatory support of the anesthetized patient markedly improves blood gas and acid-base status compared with that of the unsupported, spontaneously breathing animal.
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