• Gerardo Evaristo-Méndez, Javier Eduardo García de Alba-García, José Ernesto Sahagún-Flores, Félix Antonio Ventura-Sauceda, Jorge Uriel Méndez-Ibarra, and Rogelio Ricardo Sepúlveda-Castro.
• Departamento de Cirugía General, Hospital Regional Dr. Valentín Gómez Farías, ISSSTE. Zapopan, Jalisco, México. gevaristo5@yahoo.com.mx.
• Cir Cir. 2013 Sep 1;81(5):383-93.

BackgroundIncisional pain is the main obstacle for elective laparoscopic cholecystectomy as an outpatient. We evaluated the analgesic efficacy of local infiltration of ropivacaine with dexamethasone (Rop/Dx), compared with ropivacaine (Rop) alone, during the first 24 hours postoperative of this surgery. Our hypothesis is that incisional pain intensity will be lower in patients of the group Rop/Dx.MethodsIn a randomized, controlled, double-blind trial clinical, 80 patients were divided into two groups. Group Rop (n= 40) received pre and post-incisional infiltration with 150 mg of ropivacaine in 8 mL of 0.9% saline, while group Rop/Dx (n= 40) received 150 mg of ropivacaine with 8 mg of dexamethasone in 6 mL of 0.9% saline. The intensity of pain at rest and movement was assessed at 2, 4, 8, 12 and 24 hours postoperatively by a numerical rating scale of 11 points.ResultsIncisional pain scores in group Rop/Dx were significantly lower, compared to the group Rop, at 12 hours (p= 0.05) and 24 hours (p= 0.01) at rest and at 12 hours (p= 0.04) and 24 hours (p= 0.01) during movement postoperatively.ConclusionsWe found initial evidence that ropivacaine with dexamethasone for local infiltration decreased incisional pain intensity after 12 hours post-elective laparoscopic cholecystectomy with a good safety profile.

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