• Journal of neuro-oncology · Jan 1999

    Case Reports

    Isolated oculomotor nerve palsy: an unusual presentation of glioblastoma multiforme. Case report and review of the literature.

    • M al-Yamany, A al-Shayji, and M Bernstein.
    • Division of Neurosurgery, Toronto Hospital Western, Ontario, Canada.
    • J. Neurooncol. 1999 Jan 1;41(1):77-80.

    AbstractThe authors present a case of a very unusual clinical presentation of an intra-axial supratentorial glioblastoma multiforme (GBM) in a 63 year old diabetic female patient presenting with a three week history of left progressive complete oculomotor nerve palsy. CT scan and magnetic resonance imaging of the head revealed a left intra-axial mesial temporal glioblastoma multiforme. Operative resection and microscopic examination of a tissue specimen confirmed the diagnosis. The nature of the tumor, the pattern of spread and the postulated mechanisms of such a presentation are discussed. The authors suggest including the diagnosis of GBM in the differential diagnosis of patients with isolated complete oculomotor nerve palsy at the appropriate age group.

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