• Nature medicine · May 2012

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    Protective inflammasome activation in AMD.

    • Jing Chen and Lois E H Smith.
    • Department of Ophthalmology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA.
    • Nat. Med. 2012 May 1;18(5):658-60.

    AbstractAge-related macular degeneration (AMD) is the most common cause of blindness in the elderly. AMD progression is associated with alterations in inflammatory pathways and the immune system. A new study identifies a protective role for inflammasomes in AMD, suggesting that inflammasome activation might be manipulated as a potential therapeutic strategy for this condition (pages 791-798).

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