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- A Pancioli, T Brott, V Donaldson, and R Miller.
- Department of Emergency Medicine, University of Cincinnati College of Medicine, OH 45267-0769, USA. arthur.pancioli@oa.uc.edu
- Ann Emerg Med. 1997 Aug 1;30(2):227-9.
AbstractWe present a case of acute asymmetric angioneurotic edema associated with the use of recombinant tissue plasminogen activator (rtPA) for acute ischemic stroke. rtPA was administered for an acute ischemic stroke in accordance with the recently reported National Institute of Neurological Disorders and Stroke protocol, after which marked asymmetric angioedema requiring upper-airway control developed. Although atypical and anaphylactoid reactions have been reported with the use of rtPA for acute myocardial infarction, to our knowledge this is the first case report of asymmetric angioedema associated with the use of rtPA for acute ischemic stroke.
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