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Randomized Controlled Trial
A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zoster.
- James D Berry and Karin Lottrup Petersen.
- UCSF Pain Clinical Research Center, Department of Neurology, University of California, San Francisco, CA, USA.
- Neurology. 2005 Aug 9;65(3):444-7.
AbstractThis randomized, double-blind, placebo-controlled crossover study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster. Pain severity decreased by 66% with gabapentin compared to 33% with placebo. Reductions in allodynia area and severity, and overall pain relief, were also greater with gabapentin.
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