• Crit Care · Jan 2012

    Review

    Pro/con debate: Is etomidate safe in hemodynamically unstable critically ill patients?

    • Gordon Flynn and Yahya Shehabi.
    • Crit Care. 2012 Jan 1;16(4):227.

    AbstractEtomidate is an induction agent known for its smooth intubating conditions and cardiovascular stability. Studies, however, have shown that a single dose of etomidate can result in a prolonged adrenal insufficiency. The impact of this in patients with sepsis has been a matter for debate. This review presents a pro/con case for using etomidate in hemodynamically unstable critically ill patients and provides guidance for alternative induction techniques and when the use of etomidate might be justified despite these concerns.

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