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- Raymond Choi, Robert H Andres, Gary K Steinberg, and Raphael Guzman.
- Department of Neurosurgery, Stanford University Medical Center, Stanford, California 94305-5327, USA.
- Neurosurg Focus. 2009 May 1;26(5):E24.
AbstractIncreasing evidence in animal models and clinical trials for stroke, hypoxic encephalopathy for children, and traumatic brain injury have shown that mild hypothermia may attenuate ischemic damage and improve neurological outcome. However, it is less clear if mild intraoperative hypothermia during vascular neurosurgical procedures results in improved outcomes for patients. This review examines the scientific evidence behind hypothermia as a treatment and discusses factors that may be important for the use of this adjuvant technique, including cooling temperature, duration of hypothermia, and rate of rewarming.
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