• Naomi Ketharanathan, Mignon McCulloch, Clare Wilson, Beyra Rossouw, Shamiel Salie, Johan Ahrens, Brenda M Morrow, and Andrew C Argent.
• Division of Intensive Care and Pediatric Surgery, Department of Pediatrics, Intensive Care Unit, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, 3015GJ, The Netherlands n.ketharanathan@gmail.com.
• J. Trop. Pediatr. 2014 Dec 1;60(6):428-33.

ObjectiveFluid resuscitation is integral to resuscitation guidelines and critical care. However, fluid overload (FO) yields increased morbidity.MethodsProspective observational study of Red Cross War Memorial Children's Hospital pediatric intensive care unit admissions (February to March 2013). FO % = (fluid in minus fluid out) [liters]/weight [kg] × 100%.Primary OutcomesFO ≥ 10%, 28 day mortality.ResultsMedian [interquartile range (IQR)] age: 9.5 (2.0-39.0) months, median (IQR) admission weight: 7.9 (3.6-13.7) kg. Median (IQR) FO with admission weight: 3.5 (2.1-4.9)%; three patients had FO ≥ 10%. The 28 day mortality was 10% (n = 10). Patients who died had higher mean (IQR) FO using admission weight [4.9 (2.9-9.3)% vs. 3.4 (1.9-4.8)%; p = 0.04].ConclusionsLow FO ≥ 10% prevalence with 28 day mortality 10%. Higher FO% with admission weight associated with mortality (p = 0.04). We advocate further investigation of FO% as a simple bedside tool.© The Author [2014]. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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