• Curr Probl Diagn Radiol · Jul 2014

    Review

    Ophthalmic manifestations of systemic diseases--part 1: phakomatoses, hematologic malignancies, metastases, and histiocytosis.

    • Sanjay Sharma, Ananya Panda, Manisha Jana, Arundeep Arora, and Shefali K Sharma.
    • Department of Radiodiagnosis, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India. Electronic address: drssharma@hotmail.com.
    • Curr Probl Diagn Radiol. 2014 Jul 1;43(4):175-85.

    AbstractThe orbit can be secondarily involved in various systemic conditions. The ophthalmic involvement is often the first clue to the presence of an underlying systemic condition. The ophthalmic involvement in systemic diseases can be either ocular or extraocular. The extent of involvement can be well delineated by imaging modalities like computed tomography and magnetic resonance imaging. In the first part of the article, we provide an overview of systemic diseases affecting the orbit, briefly discuss the modalities for orbital imaging, and discuss the imaging appearances of ophthalmic involvement in (1) phakomatoses, (2) hematologic malignancies, (3) metastases, and (4) histiocytosis. At the end of the 2-part article, we discuss a pattern-based approach and differential diagnosis of orbital lesions in systemic diseases.Copyright © 2014 Elsevier Inc. All rights reserved.

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