• Clin J Pain · Nov 2007

    Randomized Controlled Trial Clinical Trial

    Effect of eutectic mixture of local anesthetics (EMLA) for pain relief during suprapubic aspiration in young infants: a randomized, controlled trial.

    • Yoav Nahum, Ariel Tenenbaum, Wexler Isaiah, and Floris Levy-Khademi.
    • Department of Pediatrics, Hadassah University Hospital, Mount Scopus Campus, Jerusalem, Israel.
    • Clin J Pain. 2007 Nov 1;23(9):756-9.

    ObjectivesThe purpose of this study was to determine whether a eutectic mixture of local anesthetics (EMLA) cream reduce the pain experienced by newborns and young infants undergoing suprapubic aspiration (SPA).MethodsA single-center, randomized, placebo-controlled, double-blind, prospective study including 52 infants 1 to 60 days of age undergoing SPA to obtain urine for culture. Twenty-four infants were randomly assigned to receive 1-g EMLA cream 1 hour before the procedure, whereas 28 were randomly assigned to receive placebo cream 1 hour before the planned procedure. Pain symptoms were measured using the Premature Infant Pain Profile (PIPP).ResultsThe mean PIPP scores were significantly lower in the EMLA group compared with the placebo group (8.90+/-3.04 vs. 10.46+/-2.29; P=0.038). There were significantly fewer patients in the EMLA group who were scored as having some degree of pain (defined as PIPP score >6) in comparison with the placebo group (70% vs. 96%; P=0.025).DiscussionNewborns and infants undergoing SPA experience pain during the procedure. Application of EMLA cream 1 hour before SPA is effective in reducing the pain associated with SPA. In situations in which an SPA is not emergent, strong consideration should be given to the use of EMLA.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…