• Crit Care · Jan 2012

    Editorial Comment

    Anemia, red blood cell transfusion, and outcomes after severe traumatic brain injury.

    • Derek J Roberts and David A Zygun.
    • Crit Care. 2012 Jan 1;16(5):154.

    AbstractIn the previous issue of Critical Care, Sekhon and colleagues report that mean 7-day hemoglobin concentration <90 g/l was associated with increased mortality among patients with severe traumatic brain injury (TBI). The adverse relationship between reduced hemoglobin concentrations and outcomes among those with TBI has been an inconsistent finding across available studies. However, as anemia is common among adults with severe TBI, and clinical equipoise may exist between specialists as to when to transfuse allogeneic red blood cells, randomized controlled trials of liberal versus restricted transfusion thresholds are indicated.

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