• Chao-Bao Luo, Michael Mu-Huo Teng, Feng-Chi Chang, Cheng-Yen Chang, and Wan-You Guo.
• Department of Radiology, Taipei Veterans General Hospital, Tapei, Taiwan, ROC. cbluo@vghtpe.gov.tw
• Otolaryngol Head Neck Surg. 2008 Jan 1;138(1):86-91.

ObjectiveTo report clinical manifestations, angiographic features, and outcomes of endovascular management in 14 patients with 15 radiation carotid blowout syndromes of nasopharyngeal carcinomas.Study Design And SubjectsRetrospective chart review of 14 patients with nasopharyngeal carcinomas (mean age 49 years) with 15 radiation carotid blowout syndromes who had undergone endovascular embolization to manage oronasal bleeding in the past 10 years.ResultsAverage radiation dose to affected carotid artery was 73 gray units (latent period: 33 months). Radiation carotid blowout syndrome was detected in internal (n = 10), external (n = 4), or common carotid artery (n = 1). Detachable balloons were used in 11 affecting arteries for vascular occlusion; 4 were treated by liquid adhesives or coil. Endovascular treatment was successful in all 15 radiation carotid blowout syndromes with cessation of hemorrhage. One patient had hemiparesis after embolization. Mean clinical follow-up was 21 months.ConclusionRadiation carotid blowout syndrome in nasopharyngeal carcinoma may occur in various periods or arteries. Endovascular embolization provides both safe and effective management.

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