• Clin. Microbiol. Infect. · Jan 2012

    Outcome of carbapenem resistant Klebsiella pneumoniae bloodstream infections.

    • D Ben-David, R Kordevani, N Keller, I Tal, A Marzel, O Gal-Mor, Y Maor, and G Rahav.
    • Infectious Diseases Unit, Sheba Medical Center, Tel Hashomer, Israel. Debby.BenDavid@sheba.health.gov.il
    • Clin. Microbiol. Infect. 2012 Jan 1;18(1):54-60.

    AbstractThe aim of this study was to evaluate the impact of carbapenem-resistant K. pneumoniae bloodstream infections on mortality. During the study period 42, 68 and 120 patients were identified with carbapenem-resistant, extended-spectrum β-lactamase producers (ESBL) and susceptible K. pneumoniae bloodstream infections, respectively. Patients with carbapenem-resistant K. pneumoniae had higher rates of prior antimicrobial exposure, other nosocomial infections, and use of invasive devices. Infection-related mortality was 48% for carbapenem-resistant, 22% for ESBL producers and 17% for susceptible K. pneumoniae. Independent risk factors for infection-related mortality were Pitt bacteraemia score, Charlson score and carbapenem resistance.© 2011 The Authors. Clinical Microbiology and Infection © 2011 European Society of Clinical Microbiology and Infectious Diseases.

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