• Crit Care · Jan 2010

    Review

    Clinical review: the ABC of weaning failure--a structured approach.

    • Johannes G van der Hoeven.
    • Department of Intensive Care Medicine (632), Radboud University Nijmegen Medical Centre, Postbox 9101, 6500 HB Nijmegen, The Netherlands. L.Heunks@ic.umcn.nl
    • Crit Care. 2010 Jan 1;14(6):245.

    AbstractAbout 20% to 30% of patients are difficult to wean from invasive mechanical ventilation. The pathophysiology of difficult weaning is complex. Accordingly, determining the reason for difficult weaning and subsequently developing a treatment strategy require a dedicated clinician with in-depth knowledge of the pathophysiology of weaning failure. This review presents a structural framework ('ABCDE') for the assessment and treatment of difficult-to-wean patients. Earlier recognition of the underlying causes may expedite weaning from mechanical ventilation.

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