• J Pain · Jun 2003

    Case Reports

    Severe intraoperative hypertension and opioid-resistant postoperative pain in a methadone-treated patient.

    • Robert Friedman, Ihab Kamel, Cara Perez, and Aboulnasr Hamada.
    • Department of Anesthesiology, Temple University Hospital, Philadelphia, Pennsylvania 19140, USA.
    • J Pain. 2003 Jun 1;4(5):289-90.

    AbstractPatients who are treated with methadone present challenges for the anesthesiologist. We report the untoward effects of rapid preoperative methadone tapering on the operative and perioperative course of a patient who required emergency surgery. The patient's exaggerated stress response to surgery and severe intractable postoperative pain might have resulted from unrecognized methadone withdrawal. Continuation of methadone treatment in patients who have surgery may prevent exaggerated intraoperative hemodynamic responses to surgical stimuli and unnecessary postoperative suffering.

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