• Debabrata Ghosh, Gayatra Mainali, Jena Khera, and Mark Luciano.
• Pediatric Neurology Center, Children's Hospital, Cleveland Clinic, Cleveland, Ohio, USA.
• Pediatr Neurosurg. 2013 Jan 1;49(3):138-44.

Background/AimsIntrathecal baclofen (ITB) therapy is useful in treating spasticity and dystonia but it has many complications, more so in children. The main aim of the study was to look at the complications of ITB pumps in children with the goal of future prevention.MethodsCharts of all patients ≤21 years with an ITB pump, implanted by a single pediatric neurosurgeon, at a single center, between 1996 and 2011 were reviewed retrospectively. Data regarding an ITB test trial were also recorded.ResultsDuring 1996-2011, 119 children (mean age 13.2 years) underwent ITB pump placement; 84% had spastic quadriplegic cerebral palsy. The gross motor function classification system level was ≥4 for most. The pump was removed in 5 (4.2%) patients due to inefficacy. The mean follow-up was 38 months. Mechanical complications requiring pump and/or catheter revision occurred in 19.3% and infections in an additional 21.8%. Seven patients (6%) had meningitis. No complication was noted after 72 months of initial pump insertion, even after pump reinsertion.ConclusionThere is a need for better infection control as well as better pump, catheter and surgical technology to lower the complications of ITB pumps in children.

30 keywords...

hide…