• J Neurosci Nurs · Oct 2003

    Review

    Pentobarbital sodium coma for refractory intracranial hypertension.

    • Joan L Censullo and Sherly Sebastian.
    • Luke's Episcopal Hospital, Houston, TX, USA. jlc_and_mlc@yahoo.com
    • J Neurosci Nurs. 2003 Oct 1;35(5):252-62.

    AbstractRefractory intracranial hypertension (RICH) is defined as intracranial pressures that exceed 25 mm Hg for 30 minutes, 30 mm Hg for 15 minutes, or 40 mm Hg for 1 minute. RICH occurs in approximately 15% of patients with traumatic brain injury. If it is not aggressively treated, RICH can result in cerebral herniation and death. Pentobarbital sodium coma is a second-tier treatment that can be used to treat RICH. Understanding the principal mechanics of this therapy is key to the successful management of RICH and quality patient care.

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