• The Journal of infection · Jan 1999

    Case Reports

    Massive pulmonary haemorrhage caused by leptospirosis successfully treated with nitric oxide inhalation and haemofiltration.

    • A Borer, I Metz, J Gilad, K Riesenberg, N Weksler, G Weber, M Alkan, and J Horowitz.
    • Infectious Disease Institute, Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
    • J. Infect. 1999 Jan 1;38(1):42-5.

    AbstractA patient with leptospirosis who developed oliguric renal failure, massive pulmonary haemorrhage and respiratory failure is described. The patient's clinical condition and arterial oxygenation failed to improve despite vigorous supportive measures. Nitric oxide inhalation and haemofiltration resulted in a marked clinical improvement and subsequent full recovery. We suggest that the addition of haemofiltration and nitric oxide inhalation therapy should be considered in patients with pulmonary haemorrhage and renal failure caused by leptospirosis, in whom conventional therapy fails.

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