• Ophthal Plast Reconstr Surg · Jan 2009

    Randomized Controlled Trial Comparative Study

    Comparison of injection pain of articaine and lidocaine in eyelid surgery.

    • Eric A Steele, John D Ng, Tasha M Poissant, and Nancy M Campbell.
    • Oregon Health and Science University, Casey Eye Institute, Portland, Oregon 97239, USA. steeleer@ohsu.edu
    • Ophthal Plast Reconstr Surg. 2009 Jan 1;25(1):13-5.

    PurposeTo compare the pain induced by tissue infiltration of lidocaine 2% with epinephrine 1:100,000 versus articaine 4% with epinephrine 1:100,000 for eyelid surgery.MethodsThirty patients undergoing bilateral eyelid surgery were enrolled in a prospective, randomized, double-masked study. Each subject received injections of lidocaine 2% with epinephrine 1:100,000 (Xylocaine) on one side and articaine 4% with epinephrine 1:100,000 (Septocaine) on the other for surgical anesthesia. The patients rated the pain of infiltration using a 100-mm visual analogue scale immediately after receiving each injection. The pain scores were compared using the paired t test.ResultsTwenty-two of the 30 patients (73.3%) rated the articaine injection as less painful than the lidocaine injection. The mean pain score for lidocaine was 42.60 +/- 24.74 and the pain score for articaine was 31.85 +/- 20.28 (p = 0.011).ConclusionsIn this study, infiltration of articaine was less painful than lidocaine for eyelid surgery, making articaine an attractive alternative for local anesthesia.

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