• Br J Anaesth · Sep 1997

    Randomized Controlled Trial Comparative Study Clinical Trial

    Rapid tracheal intubation with propofol, alfentanil and a standard dose of vecuronium.

    • R Groener and D G Moyes.
    • Department of Anaesthesia, JG Strijdom and Baragwanath Hospitals, University of the Witwatersrand, Johannesburg, South Africa.
    • Br J Anaesth. 1997 Sep 1;79(3):384-5.

    AbstractWe studied 60 ASA I patients with Mallampati grade 1 airways to compare emergency intubating conditions with either alfentanil 20 micrograms kg-1, propofol 2.5 mg kg-1 and vecuronium 0.1 mg kg-1, or with thiopentone 5 mg kg-1 and suxamethonium 1 mg kg-1. Ease of laryngoscopy, vocal cord status and cough response were graded. The trachea of all patients was intubated; 83% of patients in the alfentanil-propofol-vecuronium group and 86% in the thiopentone-suxamethonium group were considered to have satisfactory intubating conditions at 60 s. We conclude that the combination of alfentanil 20 micrograms kg-1, propofol 2.5 mg kg-1 and vecuronium 0.1 mg kg-1 provided adequate conditions for rapid tracheal intubation.

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