• Anaesth Intensive Care · Sep 2010

    Case Reports

    Estimating the net effect of unmeasured ions in human extracellular fluid using a new mathematical model. Part II: Practical issues.

    • C M Anstey.
    • Department of Critical Care Medicine, Sunshine Coast Hospital, Nambou, Queensland, Australia. chris_anstey@health.qld.gov.au
    • Anaesth Intensive Care. 2010 Sep 1;38(5):870-5.

    AbstractBuilding on the theoretical considerations developed in Part I of this two-part series, a population range was established for a new extracellular fluid acid-base parameter using Monte Carlo simulation. This new parameter the unmeasured ion excess, had a normal range of +/- 2.50 mEq/l which was slightly narrower than the normal range for the standard base excess at +/- 3.20 mmol/l. In both cases, most of this variation occurred as a result of the estimation of the bicarbonate concentration. Finally, several short clinical vignettes were explored to highlight the differences between the unmeasured ion excess and the standard base excess.

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