• Scand J Work Environ Health · Apr 1997

    Review

    Asbestos, asbestosis, pleural plaques and lung cancer.

    • G Hillerdal and D W Henderson.
    • Department of Lung Medicine, Karolinska Hospital, Stockholm, Sweden.
    • Scand J Work Environ Health. 1997 Apr 1;23(2):93-103.

    AbstractInhalation of asbestos fibers increases the risk of bronchial carcinoma. It has been claimed that asbestosis is a necessary prerequisite for the malignancy, but epidemiologic studies usually do not have enough statistical strength to prove that asbestos-exposed patients without asbestosis are without risk. Several recent studies do actually indicate that there is a risk for such patients. In addition, case-referent studies of patients with lung cancer show an attributable risk for asbestos of 6% to 23%, which is much higher than the actual occurrence of asbestosis among these patients. Thus there is an increasing body of evidence that, at low exposure levels, asbestos produces a slight increase in the relative risk of lung cancer even in the absence of asbestosis. Consequently, all exposure to asbestos must be minimized.

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