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Case Reports
Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the thoracic spine.
- Elena Pirola, Francesco Vergani, Paolo Casiraghi, Eugenio Biagio Leone, Paolo Guerra, and Erik Pietro Sganzerla.
- Neurosurgery, University of Milano-Bicocca, Monza, Italy. oxosintesi@libero.it
- J Neurosurg Spine. 2009 Apr 1;10(4):329-33.
AbstractPhosphaturic mesenchymal tumors that cause the paraneoplastic syndrome known as oncogenic osteomalacia are rare. The authors report on the case of a 57-year-old man with a history of osteomalacia and in whom was diagnosed a thoracic spine tumor at the T-4 level. Complete tumor resection was accomplished. The histological diagnosis was phosphaturic mesenchymal tumor (mixed connective tissue variant). After lesion removal, the paraneoplastic syndrome resolved. At the 24-month follow-up, no recurrence of the disease was observed. The clinical presentation, surgical technique, and follow-up in this case were reviewed in detail.
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