• Best Pract Res Clin Anaesthesiol · Mar 2014

    Review

    Multimodal therapy in perioperative analgesia.

    • Karina Gritsenko, Yury Khelemsky, Alan David Kaye, Nalini Vadivelu, and Richard D Urman.
    • Department of Anesthesiology, Montefiore Medical Center, Bronx, New York, NY, USA; Department of Family and Social Medicine, Montefiore Medical Center, Bronx, New York, NY, USA; Acute Pain, Regional, Chronic Pain, Montefiore Medical Center, Bronx, New York, NY, USA; Albert Einstein College of Medicine, Yeshiva University, Montefiore Medical Center, Bronx, New York, NY, USA. Electronic address: karina.gritsenko@gmail.com.
    • Best Pract Res Clin Anaesthesiol. 2014 Mar 1; 28 (1): 59-79.

    AbstractThis article reviews the current evidence for multimodal analgesic options for common surgical procedures. As perioperative physicians, we have come a long way from using only opioids for postoperative pain to combinations of acetaminophen, nonsteroidal anti-inflammatory drugs (NSAIDs), selective Cyclo-oxygenase (COX-2) inhibitors, local anesthetics, N-methyl-d-aspartate (NMDA) receptor antagonists, and regional anesthetics. As discussed in this article, many of these agents have decreased narcotic requirements, improved patient satisfaction, and decreased postanesthesia care unit (PACU) times, as well as morbidity in the perioperative period. Published by Elsevier Ltd.

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