• Middle East J Anaesthesiol · Jun 2008

    Comparative Study

    Hemodynamic effects of anesthetic induction in patients treated with beta and calcium channel blockers.

    • Khalid Samad, Fawzia Khan, and Iqbal Azam.
    • Dept. of Anaesthesia, Agha Khan Univ., Karachi, Pakistan. khalid.samad@aku.edu
    • Middle East J Anaesthesiol. 2008 Jun 1;19(5):1111-28.

    BackgroundThe response to anesthetic induction and airway manipulation in the presence of cardiovascular disease and antihypertensive therapy has not been adequately investigated.MethodsThe blood pressure, pulse pressure and heart rate changes at induction and following tracheal intubation were compared in patients who were on either preoperative beta-adrenergic blocker therapy (BB group, n = 20) or a combination of beta-adrenergic blocker and calcium channel blocker therapy (BB + CCB group, n = 20). A standardized anesthesia induction protocol was followed, in the two gourps.ResultsNo statistical difference was observed in the hemodynamic parameters between the two groups. The total number of hypotensive patients (SAP 90 ConclusionHypotension requiring treatment in patients receiving a combination of BB + CCB is more frequent after induction of anesthesia.

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