• Pediatric dermatology · Jul 2003

    Randomized Controlled Trial Multicenter Study Clinical Trial

    Lidocaine iontophoresis for topical anesthesia before dermatologic procedures in children: a randomized controlled trial.

    • William T Zempsky and Thomas M Parkinson.
    • Department of Pediatrics, University of Connecticut School of Medicine, Hartford, CT, USA. wzempsk@ccmckids.org
    • Pediatr Dermatol. 2003 Jul 1;20(4):364-8.

    AbstractLocal anesthesia by injection in pediatric patients undergoing dermatologic procedures is not well received because of the pain of injection and the fear of needles. Lidocaine iontophoresis is a method of topical anesthesia where lidocaine is driven into the skin under the influence of electric current. We performed a prospective double-blind, placebo-controlled evaluation of iontophoresis of 2% lidocaine with 1:100,000 epinephrine. Sixty children requiring dermatologic procedures were enrolled (50 shave biopsy, 7 curettage, 2 injection, 1 punch biopsy). Twenty-nine of 31 patients in the lidocaine group versus 2 of 29 placebo patients required no supplemental anesthesia (p < 0.001). The pain reported by the patients on the Oucher pain scale subsequent to the procedure was significantly lower in the lidocaine group (p < 0.001). Investigators and parents also rated pain lower in the lidocaine group (p < 0.001). Blanching and/or erythema occurred in 58 of 60 patients, but resolved within 1 hour in all patients. There were no other adverse events. Lidocaine iontophoresis is a safe and effective method of topical anesthesia prior to dermatologic procedures in children.

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