• Jeffrey J Tosoian, Caitlin W Hicks, John L Cameron, Vicente Valero, Frederic E Eckhauser, Kenzo Hirose, Martin A Makary, Timothy M Pawlik, Nita Ahuja, Matthew J Weiss, and Christopher L Wolfgang.
• Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland.
• JAMA Surg. 2015 Feb 1;150(2):152-8.

ImportanceReadmission after pancreatectomy is common, but few data compare patterns of readmission to index and nonindex hospitals.ObjectivesTo evaluate the rate of readmission to index and nonindex institutions following pancreatectomy at a tertiary high-volume institution and to identify patient-level factors predictive of those readmissions.Design, Setting, And ParticipantsRetrospective analysis of a prospectively collected institutional database linked to statewide data of patients who underwent pancreatectomy at a tertiary care referral center between January 1, 2005, and December 2, 2010.ExposurePancreatectomy.Main Outcomes And MeasuresThe primary outcome was unplanned 30-day readmission to index or nonindex hospitals. Risk factors and reasons for readmission were measured and compared by site using univariable and multivariable analyses.ResultsAmong all 623 patients who underwent pancreatectomy during the study period, 134 (21.5%) were readmitted to our institution (105 [78.4%]) or to an outside institution (29 [21.6%]). Fifty-six patients (41.8%) were readmitted because of a gastrointestinal or nutritional problem related to surgery and 42 patients (31.3%) because of a postoperative infection. On multivariable analysis, factors independently associated with readmission included age 65 years or older (odds ratio [OR], 1.80; 95% CI, 1.19-2.71), preexisting liver disease (OR, 2.28; 95% CI, 1.23-4.24), distal pancreatectomy (OR, 1.77; 95% CI, 1.11-2.84), and postoperative drain placement (OR, 2.81; 95% CI, 1.00-7.14).Conclusions And RelevanceIn total, 21.5% of patients required early readmission after pancreatectomy. Even in the setting of a tertiary care referral center, 21.6% of these readmissions were to nonindex institutions. Specific patient-level factors were associated with an increased risk of readmission.

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