Late-onset sepsis in a preterm twin may harbinger

Pediatr. Infect. Dis. J. · Apr 2010

Case Reports

Late-onset sepsis in a preterm twin may harbinger life-threatening sepsis for the asymptomatic co-twin.

We report extremely preterm twins who developed late-onset Escherichia coli sepsis in the second postnatal week within a short time of each other. The asymptomatic twin was not treated initially, and within 2 days developed life-threatening septicemia and meningitis, followed by other serious morbidity. Occurrence of late-onset sepsis in a twin should prompt concurrent investigation and consideration of presumptive treatment of the apparently asymptomatic co-twin.

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- Jayaram R Pai, Catherine H Tremlett, and Paul Clarke.
- Neonatal Intensive Care Unit, Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, United Kingdom.
- Pediatr. Infect. Dis. J. 2010 Apr 1;29(4):381-2.
AbstractWe report extremely preterm twins who developed late-onset Escherichia coli sepsis in the second postnatal week within a short time of each other. The asymptomatic twin was not treated initially, and within 2 days developed life-threatening septicemia and meningitis, followed by other serious morbidity. Occurrence of late-onset sepsis in a twin should prompt concurrent investigation and consideration of presumptive treatment of the apparently asymptomatic co-twin.

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Late-onset sepsis in a preterm twin may harbinger life-threatening sepsis for the asymptomatic co-twin.

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