• Biomarkers in medicine · Jan 2014

    Review

    What can we expect from biomarkers for acute kidney injury?

    • John A Kellum and Prasad Devarajan.
    • Center for Critical Care Nephrology, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 604, Scaife Hall, 3550 Terrace Street, Pittsburgh, PA 15261, USA.
    • Biomark Med. 2014 Jan 1;8(10):1239-45.

    AbstractBiomarkers for acute kidney injury have numerous potential roles to play both at the bedside and in the design and conduct of clinical trials. Given the heterogeneous nature of this disease and the difficulty, so far, in developing effective therapies, a strategy that deploys all of our available tools in the treatment and in study of treatments would seem prudent. In this review, we discuss how biomarkers will change the way we do we take care of patients with and do clinical trials in acute kidney injury and why, in fact, biomarkers are necessary.

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