• JAMA · Nov 2015

    Comment

    Interventions for Hirsutism.

    • Esther J van Zuuren and Zbys Fedorowicz.
    • Department of Dermatology, Leiden University Medical Centre, Leiden, the Netherlands.
    • JAMA. 2015 Nov 3;314(17):1863-4.

    Clinical QuestionWhat medical therapies are associated with greatest efficacy and fewest adverse events for treating hirsutism?Bottom LineOral contraceptive pills (OCPs) have been associated with improvement for mild hirsutism, as has flutamide (250 mg) twice daily and spironolactone for more severe cases. Finasteride and gonadotropin-releasing analogues are associated with inconsistent results and metformin is not associated with benefit.

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