• Respiratory care · Apr 2016

    Influence of Time and Frequency of Passive Smoking Exposure on Mucociliary Clearance and the Autonomic Nervous System.

    • Ana Paula Cf Freire, Dionei Ramos, Marceli R Leite, Bruna Sa Silva, Renata M David, Juliana S Uzeloto, Francis L Pacagnelli, Luiz Carlos M Vanderlei, and Ercy Mara C Ramos.
    • postgraduate Physical Therapy Program, São Paulo State University, Presidente Prudente, São Paulo, Brazil. anapcff@hotmail.com.
    • Respir Care. 2016 Apr 1; 61 (4): 453-61.

    BackgroundThere are still gaps in the knowledge regarding the damage to mucociliary and autonomous systems from passive exposure to cigarette smoke. Also, the influence of the frequency and duration of exposure on these systems is still unclear. The objective of this work was to verify the effects of passive smoking on mucociliary clearance and adult autonomic nervous systems and investigate the influence of frequency and time of passive exposure on these systems.Methods44 smokers (smoking group), 38 passive smokers (passive smoking group), and 38 healthy individuals (control group) were evaluated. Evaluation of lung function was performed. To analyze the autonomic nervous system, heart rate variability data were collected. Hemodynamic parameters were collected. Mucociliary clearance was evaluated using the saccharin transit time test.ResultsThe passive smoking group presented reduced lung function (P = .02). Systolic blood pressure was significantly greater in the passive smoking group when compared with the smoking group (P = .02). The passive smoking group presented significantly slower transportability time than the control group. No differences were observed between the groups for the heart rate variability data. There was a significant correlation (P < .05) between the frequency of exposure and diastolic blood pressure, oxygen saturation, and FEF(25-75%). Correlation analyses also demonstrated a reduction of global autonomic activity according to exposure load, in addition to a reduction in vagal activity and an increase in sympathetic activity according to exposure frequency.ConclusionsPassive smokers presented worse mucociliary clearance, and there was a correlation between passive exposure load and damage to the hemodynamic response, pulmonary function and autonomic nervous system.Copyright © 2016 by Daedalus Enterprises.

      Pubmed     Free full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…