• Critical care clinics · Apr 2010

    Optimizing hemodynamic support in septic shock using central and mixed venous oxygen saturation.

    • Supriya Maddirala and Akram Khan.
    • Division of Nephrology, Department of Internal Medicine, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA.
    • Crit Care Clin. 2010 Apr 1; 26 (2): 323-33, table of contents.

    AbstractGlobal tissue hypoxia is one of the most important factors in the development of multisystem organ dysfunction. In hemodynamically unstable critically ill patients, central venous oxygen saturation (Scvo(2)) and mixed venous oxygen saturation (Svo(2)) monitoring has been shown to be a better indicator of global tissue hypoxia than vital signs and other clinical parameters alone. Svo(2) is probably more representative of global tissue oxygenation, whereas Scvo(2), is less invasive. Svo(2) and Scvo(2) monitoring can have diagnostic and therapeutic uses in understanding the efficacy of interventions in treating critically ill, hemodynamically unstable patients.Copyright 2010 Elsevier Inc. All rights reserved.

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