• The Journal of pediatrics · Aug 2014

    Randomized Controlled Trial

    School-age outcomes following a randomized controlled trial of magnesium sulfate for neuroprotection of preterm infants.

    • Clément Chollat, Maya Enser, Estelle Houivet, Delphine Provost, Jacques Bénichou, Loïc Marpeau, and Stéphane Marret.
    • Department of Neonatal Pediatrics and Intensive Care, Rouen University Hospital, Rouen, France; Region INSERM Team 28 "NeoVasc", Laboratory of Microvascular Endothelium and Neonate Brain Lesions, Institute for Biomedical Research, Rouen University, Rouen, France. Electronic address: clement.chollat@chu-rouen.fr.
    • J. Pediatr. 2014 Aug 1;165(2):398-400.e3.

    AbstractIn a French randomized trial, children at school-age demonstrated no evidence of harm from fetal exposure to MgSO4 before very preterm birth. Motor dysfunction/death, qualitative behavioral disorders, cognitive difficulties, school grade repetition, and education services were decreased in the children exposed to MgSO4, although the differences were not significant.Copyright © 2014 Elsevier Inc. All rights reserved.

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