• Ana Miriam Velly, John O Look, Eric Schiffman, Patricia A Lenton, Wenjun Kang, Ronald P Messner, Christina A Holcroft, and James R Fricton.
• Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, Minnesota 55455, USA. velly001@umn.edu
• J Pain. 2010 Nov 1; 11 (11): 1155-64.

UnlabelledAlthough most cases of temporomandibular muscle and joint disorders (TMJD) are mild and self-limiting, about 10% of TMJD patients develop severe disorders associated with chronic pain and disability. It has been suggested that fibromyalgia and widespread pain play a significant role in TMJD chronicity. This paper assessed the effects of fibromyalgia and widespread pain on clinically significant TMJD pain (GCPS II-IV). Four hundred eighty-five participants recruited from the Minneapolis/St. Paul area through media advertisements and local dentists received examinations and completed the Graded Chronic Pain Scale (GCPS) at baseline and at 18 months. Baseline widespread pain (OR: 2.53, P = .04) and depression (OR: 5.30, P = .005) were associated with onset of clinically significant pain (GCPS II-IV) within 18 months after baseline. The risk associated with baseline fibromyalgia was moderate, but not significant (OR: 2.74, P = .09). Persistence of clinically significant pain was related to fibromyalgia (OR: 2.48, P = .02) and depression (OR: 2.48, P = .02). These results indicate that these centrally generated pain conditions play a role in the onset and persistence of clinically significant TMJD.PerspectiveFibromyalgia and widespread pain should receive important consideration when evaluating and developing a treatment plan for patients with TMJD.Copyright © 2010 American Pain Society. Published by Elsevier Inc. All rights reserved.

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